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The product has been designed for patients using glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide therapies, which are increasingly being adopted globally for weight-loss and diabetes treatment

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Nuclear IGF1R is a transcriptional co-activator of LEF1/TCF

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This receptor is essential for life (20), is expressed throughout ontogeny (21, 22, 23), and available human single-cell RNA information indicates the highest expression in nerve cells, but all types of cells and tissues express it ( These characteristics bespeak the biological relevance of IGF-1 signaling